Why the study?
Does graded lower body negative pressure alter cardiovascular autonomic responses in patients with diabetes mellitus compared to normal subjects?
Population
Patients with diabetes mellitus and normal non-diabetic subjects
Comparison
Graded increments of lower body negative… vs Normal non-diabetic subjects
Design
Cross-sectional
Authors
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Impaired baroreflex sensitivity, especially R-R control, may precede vasomotor dysfunction in diabetic neuropathy; hypothesis-generating and requires prospective validation.
Does graded lower body negative pressure alter cardiovascular autonomic responses in patients with diabetes mellitus compared to normal subjects?
The study suggests that in diabetic autonomic neuropathy, impairment of heart-rate control occurs earlier than impairment of vasomotor function.
Bennett et al. (1980) studied this question.
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