Why the study?
Does monitoring digoxin concentrations in protein-free ultrafiltrates eliminate interference from DLISs in patients undergoing therapeutic digoxin monitoring?
Population
Patients with volume-expanded conditions or those ingesting Chinese medicines, spironolactone, canrenone, or…
Comparison
Monitoring digoxin concentrations in… vs Standard serum digoxin measurement
Design
Review
Authors
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May reduce DLIS assay interference via ultrafiltrates; hypothesis-generating and requires prospective validation before practice change.
Does monitoring digoxin concentrations in protein-free ultrafiltrates eliminate interference from DLISs in patients undergoing therapeutic digoxin monitoring?
Monitoring digoxin in protein-free ultrafiltrates eliminates assay interference from endogenous and exogenous digoxin-like immunoreactive substances.
Amitava Dasgupta (2002) studied this question.
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