February 1, 2002Pacing and Clinical Electrophysiology
Alternans in QRS Amplitude During Ventricular Tachycardia
Why the study?
Does the presence of QRS alternans during ventricular tachycardia predict failure of antitachycardia pacing and lack of spontaneous termination in patients with implantable defibrillators?
Population
25 patients with 111 episodes of spontaneous monomorphic regular ventricular tachycardia retrieved from…
Comparison
Presence of QRS alternans during VT vs Absence of QRS alternans (nonalternans VT)
Design
Cohort
Authors
Discussion
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Implication
QRS alternans in VT was associated with higher ATP failure and absent spontaneous termination; hypothesis-generating for ICD programming, needs prospective validation.
Structured PICO
Does the presence of QRS alternans during ventricular tachycardia predict failure of antitachycardia pacing and lack of spontaneous termination in patients with implantable defibrillators?
P
Population
25 patients with 111 episodes of spontaneous monomorphic regular ventricular tachycardia (VT) retrieved from implantable defibrillators
I
Intervention
Presence of QRS alternans during VT (detected via spectral analysis of intracardiac electrograms)
C
Comparator
Absence of QRS alternans (nonalternans VT)
O
Outcome
Failure of antitachycardia pacing and spontaneous termination of VTsurrogate
QRS alternans during ventricular tachycardia is a relatively common finding that may predict failure of antitachycardia pacing and lack of spontaneous termination.
Cite This Study
Maury et al. (2002) studied this question.