Why the study?
Does T wave alternans (TWA) measured from ICD electrograms predict spontaneous ventricular tachyarrhythmias in defibrillator recipients?
Population
74 patients with implantable cardioverter defibrillators (ICD), mean age 55.3+/-12.2 years, 59 males.
Comparison
Measurement of T wave alternans, Tpte interval… vs Measurement immediately after ICD shocks during…
Design
Cohort
Authors
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TWA on ICD electrograms precedes spontaneous VT; hypothesis-generating for repolarization-based prediction but should not yet change practice.
Does T wave alternans (TWA) measured from ICD electrograms predict spontaneous ventricular tachyarrhythmias in defibrillator recipients?
T wave alternans measured from ICD electrograms immediately precedes spontaneous VT, suggesting repolarization alternans plays an important role in VT induction.
Kim et al. (2008) studied this question.
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