Why the study?
Does increased maternal parity increase the risk of congenital heart defects in offspring?
Population
19 observational studies assessing the association between maternal parity and congenital heart defect risk…
Comparison
Maternal parity vs Nulliparous women or lowest parity number
Design
Meta-analysis
Authors
Loading...
Supports parity in preconception CHD risk discussions; leaves open causality and need for prospective confirmation.
Does increased maternal parity increase the risk of congenital heart defects in offspring?
Higher maternal parity is associated with a dose-dependent increase in the risk of congenital heart defects in offspring.
Feng et al. (2014) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: