Population
ATP-dependent potassium channels from rat skeletal muscle using inside-out excised sarcolemmal patches
Design
Preclinical
Authors
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Advances KATP channel biophysics in skeletal muscle; leaves open translation to human cardiac physiology.
The study provides a rate theory model explaining the voltage-dependent block of KATP channels by intracellular Mg2+ in rat skeletal muscle, highlighting an asymmetrical inner energy barrier.
Davies et al. (1996) studied this question.
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