Why the study?
Platelet activation contributes to organ failure in endotoxemia, but the role of clopidogrel in modulating the inflammatory progression of endotoxemia remains largely unexplored.
Does clopidogrel reduce inflammation and platelet activation in an experimental endotoxemic mouse model?
Does clopidogrel reduce inflammation and platelet activation in an experimental endotoxemic mouse model?
Clopidogrel reduces platelet activation and inflammatory processes in an experimental mouse model of endotoxemia.
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Clopidogrel may attenuate experimental endotoxemic injury; hypothesis-generating for clinical sepsis trials.
Wang et al. (2018) studied this question.
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