March 1, 1976JAMA
Nitrous Oxide as an Analgesic in Acute Myocardial Infarction
Why the study?
Does nitrous oxide 35% ameliorate pain in patients with acute myocardial infarction?
Population
111 patients with acute myocardial infarction
Design
RCT, double-blind
Authors
Discussion
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Member takes
Implication
Offers safe analgesia for acute MI; strengthens randomized evidence for emergency cardiac protocols.
Structured PICO
Does nitrous oxide 35% ameliorate pain in patients with acute myocardial infarction?
P
Population
111 patients with acute myocardial infarction (69 in a double-blind study and 42 in an additional clinical study)
I
Intervention
Nitrous oxide in a concentration of 35%
O
Outcome
Pain ameliorationpatient reported
Nitrous oxide 35% provides safe and effective analgesia for patients experiencing acute myocardial infarction.
Cite This Study
Peter L. Thompson (1976) studied this question.