Why the study?
Are viral isolation rates from throat and rectal swabs higher in children with acute upper respiratory tract infection compared to healthy children?
Population
206 children: 103 with acute upper respiratory tract infection and 103 healthy children matched for age and…
Comparison
Throat and rectal swabs for viral isolation vs Healthy children matched for age and sex
Design
Case-control
Authors
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Throat swabs may better implicate enteroviruses in pediatric URI than rectal; case-control data leaves open causality and clinical adoption.
Are viral isolation rates from throat and rectal swabs higher in children with acute upper respiratory tract infection compared to healthy children?
Enteroviruses play a pathogenic role in pediatric URI, and throat swabs are more etiologically significant than rectal swabs for viral isolation.
Kepfer et al. (1974) studied this question.
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