Why the study?
Does phentolamine alter forearm venous distensibility in young men with borderline hypertension compared to normotensive controls?
Does phentolamine alter forearm venous distensibility in young men with borderline hypertension compared to normotensive controls?
Young men with borderline hypertension exhibit decreased venous distensibility that is partly mediated by alpha-adrenergic venoconstriction and partly by non-adrenergic mechanisms.
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Reduced venous distensibility may mark early hypertension; leaves open causal direction and reversibility with alpha-blockade.
Takeshita et al. (1979) studied this question.
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