Population
Hep G2 cells
Comparison
Oleic acid treatment vs Untreated cells (implied)
Design
Preclinical
Authors
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May inform hepatic phospholipid regulation mechanisms but should not change practice; leaves open relevance to cardiovascular lipid metabolism in vivo.
Oleic acid promotes the formation of active cytidylyltransferase (H-form) from a preexisting inactive form in Hep G2 cells, thereby increasing phosphatidylcholine synthesis.
Weinhold et al. (1991) studied this question.
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