December 21, 2020Circulation
Effects of Fentanyl Versus Morphine on Ticagrelor-Induced Platelet Inhibition in Patients With ST-Segment Elevation Myocardial Infarction
Why the study?
Does fentanyl compared to morphine improve ticagrelor-induced platelet inhibition in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention?
Population
Patients with STEMI undergoing primary PCI
Comparison
Fentanyl vs morphine with pre-hospital ticagrelor
Design
Trial
Authors
Discussion
Loading...
Member takes
Implication
Opioid choice may influence ticagrelor response in STEMI PCI; leaves open optimal agent pending randomized trials.
Structured PICO
Does fentanyl compared to morphine improve ticagrelor-induced platelet inhibition in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention?
P
Population
Patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention
I
Intervention
Fentanyl (with pre-hospital ticagrelor)
C
Comparator
Morphine (with pre-hospital ticagrelor)
O
Outcome
Ticagrelor-induced platelet inhibitionsurrogate
This study investigates the comparative effects of fentanyl versus morphine on ticagrelor-induced platelet inhibition in STEMI patients undergoing primary PCI.
Cite This Study
Iglesias et al. (2020) studied this question.