Why the study?
Is baroreceptor sensitivity reduced in patients with chronic obstructive pulmonary disease compared to normal subjects?
Population
27 patients with chronic obstructive pulmonary disease and 10 normal subjects of comparable age (total n=37).
Design
Case-control
Authors
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Reduced baroreflex sensitivity may signal autonomic dysfunction in COPD; leaves open prognostic value and therapeutic implications.
Is baroreceptor sensitivity reduced in patients with chronic obstructive pulmonary disease compared to normal subjects?
Baroreflex sensitivity is attenuated in patients with COPD, likely driven primarily by pulmonary hypertension and partly by hypoxia and hypercapnia.
Patakas et al. (1982) studied this question.
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