August 1, 1983Circulation
Arterial baroreflex sensitivity, plasma catecholamines, and pressor responsiveness in essential hypertension.
Population
54 subjects (25 patients with essential hypertension and 29 normotensive control subjects)
Design
Case-control
Authors
Discussion
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Member takes
Implication
Supports autonomic dysfunction in hypertension maintenance; hypothesis-generating, requiring longitudinal studies before clinical implications.
Structured PICO
P
Population
54 subjects (25 patients with essential hypertension and 29 normotensive control subjects)
C
Comparator
Normotensive control subjects
O
Outcome
Arterial baroreflex sensitivity, plasma norepinephrine and epinephrine levels, and pressor/depressor responsessurrogate
Patients with essential hypertension exhibit decreased baroreflex-cardiac sensitivity, increased sympathetic outflow, and pressor hyperresponsiveness compared to normotensive controls.
Cite This Study
David S. Goldstein (1983) studied this question.