Why the study?
Is baroreflex control of sympathetic nerve activity altered in patients with essential hypertension during blood pressure changes?
Population
23 normotensive subjects and 23 patients with essential hypertension
Comparison
Intravenous injection of phenylephrine and… vs Normotensive subjects
Design
Cross-sectional
Authors
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Blunted baroreflex sympathoinhibition may sustain hypertension; leaves open causality and needs prospective confirmation before clinical consideration.
Is baroreflex control of sympathetic nerve activity altered in patients with essential hypertension during blood pressure changes?
Patients with essential hypertension exhibit a blunted baroreflex-mediated decrease in sympathetic nerve activity during blood pressure elevation, which may contribute to the maintenance of elevated blood pressure.
Matsukawa et al. (1991) studied this question.
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