November 1, 1981HypertensionOpen Access

Mechanoelastic properties of the aorta in chronically hypertensive conscious rats.

View Full Paper

Ask AI

Bookmark

Population

11 normotensive (NCR) and 17 one-kidney, one clip chronic renal hypertensive conscious Wistar rats (RHR)

Comparison

One-kidney, one clip chronic renal hypertension… vs Normotensive Wistar rats

Design

Preclinical

Authors

LMLisete Compagno MicheliniPreventive Cardiology EKEduardo Moacyr KriegerHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

Discussion

Member takes

Implication

Aortic adaptations in hypertensive rats warrant no clinical action; leaves open mechanistic links to baroreceptor resetting in humans.

Structured PICO

Population

11 normotensive (NCR) and 17 one-kidney, one clip chronic renal hypertensive conscious Wistar rats (RHR)

Intervention

One-kidney, one clip chronic renal hypertension model

Comparator

Normotensive Wistar rats

Outcome

Relationship between aortic caliber (AC) and aortic pressure (AP) at rest and during transient changes in blood pressuresurrogate

Chronic renal hypertensive rats exhibit increased aortic caliber, pressure, and thickness, but maintain similar dynamic distensibility and mean strain compared to normotensive rats, which may be important for baroreceptor resetting.

Cite This Study

Michelini et al. (1981) studied this question.

synapsesocial.com/papers/6a854063f14ace264a43d60a https://doi.org/10.1161/01.hyp.3.6_pt_2.ii-177

Topics

Hypertension management

View Full Paper

Ask AI

Bookmark

Mechanoelastic properties of the aorta in chronically hypertensive conscious rats.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Mechanoelastic properties of the aorta in chronically hypertensive conscious rats.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider