Why the study?
Does obesity alter insulin levels, renal sodium handling, and sympathetic nerve activity in normotensive subjects?
Does obesity alter insulin levels, renal sodium handling, and sympathetic nerve activity in normotensive subjects?
In normotensive subjects, obesity is associated with hyperinsulinemia and altered renal sodium handling, though without a direct correlation between insulin levels and sodium excretion.
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Obesity links to hyperinsulinemia and reduced sodium excretion in normotensives without direct correlation; hypothesis-generating for hypertension mechanisms, needs prospective confirmation.
Wada et al. (1992) studied this question.
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