December 1, 1998AJP Regulatory Integrative and Comparative Physiology

Regulation of the sympathetic nerve discharge bursting pattern during heat stress

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Why the study?

Does heat stress alter the sympathetic nerve discharge bursting pattern in chloralose-anesthetized rats?

Population

chloralose-anesthetized rats

Comparison

Heat stress vs Baseline core body temperature (38 degrees C)

Design

Preclinical

Authors

MKMichael KenneyThe University of Texas at El Paso DCDale E. ClaassenKansas State University MBMichelle R. BishopKansas State University

Discussion

Member takes

Implication

Caution against human extrapolation from rats; extends rodent models of hyperthermia-induced sympathetic reorganization.

Structured PICO

Does heat stress alter the sympathetic nerve discharge bursting pattern in chloralose-anesthetized rats?

Population

chloralose-anesthetized rats

Intervention

Heat stress (increases in core body temperature from 38 to 41.4 +/- 0.3 degrees C)

Comparator

Baseline core body temperature (38 degrees C)

Outcome

Sympathetic nerve discharge (SND) bursting pattern and frequency-domain relationshipssurrogate

Acute heat stress profoundly alters the organization of neural circuits responsible for sympathetic nerve activity, providing a mechanism for increasing sympathetic activity during hyperthermia.

Cite This Study

Kenney et al. (1998) studied this question.

synapsesocial.com/papers/6a854487ff13e6e4e743dcd0 https://doi.org/10.1152/ajpregu.1998.275.6.r1992

View Full Paper

Ask AI

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Regulation of the sympathetic nerve discharge bursting pattern during heat stress

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Regulation of the sympathetic nerve discharge bursting pattern during heat stress

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider