Why the study?
Does acidosis mediate the excitation of afferent cardiac sympathetic nerve fibers during myocardial ischemia in anesthetized dogs?
Does acidosis mediate the excitation of afferent cardiac sympathetic nerve fibers during myocardial ischemia in anesthetized dogs?
Acidosis appears to mediate the excitation of unmyelinated, but not myelinated, afferent sympathetic nerve fibers during myocardial ischemia.
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Acidosis may selectively drive unmyelinated cardiac afferent excitation in ischemia; leaves open translation to human sympathetic activation or symptoms.
Uchida et al. (1975) studied this question.
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