Population
Mengovirus mutants with overlapping deletions within the 2A region, and two chimeric constructs
Comparison
Genetic mutation/deletion or chimeric… vs Wild-type mengovirus
Design
Preclinical
Authors
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Mengovirus 2A supports efficient virus production; animal data leaves open its targeting in human cardioviruses.
Mengovirus 2A plays a functional role in virus translation or replication, and its processing cascade occurs sequentially.
Zoll et al. (1998) studied this question.
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