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March 29, 2012European Heart Journal - Cardiovascular Imaging

Among 1114 patients with a zero CCS, obstructive CAD was found in 4.3% (48 patients), with 2.2% undergoing early revascularization and 1.3% experiencing major adverse cardiac events during follow-up.

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Why the study?

Does a zero coronary calcium score exclude obstructive CAD and adverse cardiac events in symptomatic patients with chest pain?

Population

2088 symptomatic patients with chest pain syndrome referred for 64-slice coronary computed tomographic…

Design

Cohort

Follow-up

1033 ± 136 days

Authors

YKYoung Jin KimJHJin HurHLHye‐Jeong Lee

Discussion

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Overview

Zero CCS does not exclude obstructive CAD or MACE in symptomatic patients; leaves open whether calcium scoring alone suffices for risk stratification.

Structured PICO

Does a zero coronary calcium score exclude obstructive CAD and adverse cardiac events in symptomatic patients with chest pain?

P
Population
2088 symptomatic patients with chest pain syndrome referred for 64-slice coronary computed tomographic (CT) angiography, mean age 58 ± 10 years, 1028 men.
I
Intervention
Coronary calcium score (CCS) of zero
O
Outcome
Prevalence of obstructive coronary artery disease (CAD)surrogate

A zero coronary calcium score does not definitively exclude obstructive CAD or future adverse cardiac events in symptomatic patients presenting with chest pain.

Cite This Study

Kim et al. (2012) studied this question.

synapsesocial.com/papers/6a85493b38b24859dfd6ad20https://doi.org/10.1093/ehjci/jes060
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A zero coronary artery calcium score in patients with stable chest pain is associated with a good prognosis, despite risk of non-calcified plaques2019 · 47 citations
  2. 2Assessing the reliability of coronary artery calcium score in symptomatic patients: challenging the 'power of zero'2024 · 1 citations
  3. 3Coronary calcium to rule out obstructive coronary artery disease in patients with non-anginal chest pain2026 · 1 citations
  4. 4Role of Coronary Calcium Score as a Screening Tool for Excluding Significant Coronary Artery Disease in High Risk Asymptomatic Patients2022
  5. 5Prevalence of coronary artery stenosis on computed tomography angiography of the coronary arteries in stable patients with zero coronary calcium score in Angola2023