Why the study?
Coronary artery calcium marks atherosclerosis and CAD, and the study sought to assess the prevalence of CAD in patients with a zero CCS using 64-slice CT in Angola.
What is the prevalence of coronary artery stenosis on computed tomography angiography in stable patients with a zero coronary calcium score?
Population
204 stable patients undergoing coronary CT angiography in Angola
Comparison
CCS=0 vs CCS ≥1
Design
Observational cross-sectional study
Key result
A coronary calcium score of zero was associated with a very low prevalence of significant coronary artery disease (0.7%) compared to patients with a score ≥1 (33.8%).
Authors
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Zero CCS tied to low obstructive CAD risk in Angola; hypothesis-generating for CT screening in African populations.
Cross-Sectional (n=204)
No
What is the prevalence of coronary artery stenosis on computed tomography angiography in stable patients with a zero coronary calcium score?
Absolute Event Rate: 0.7% vs 33.8%
p-value: p=<0.001
In stable patients in Angola, a zero coronary calcium score is associated with a very low probability (0.7%) of obstructive coronary artery disease, supporting its high negative predictive value.
Morais et al. (2023) conducted a cross-sectional in Suspected coronary artery disease (n=204). Coronary calcium score of zero vs. Coronary calcium score ≥1 was evaluated on Significant coronary artery disease (>50% stenosis) (p=<0.001). A coronary calcium score of zero was associated with a very low prevalence of significant coronary artery disease (0.7%) compared to patients with a score ≥1 (33.8%).
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