Why the study?
Do specific amino acids and their analogues inhibit the propagation of mouse encephalomyelitis virus in tissue cultures?
Population
Tissue cultures of one-day-old mouse brain infected with Theiler's GDVII strain of mouse encephalomyelitis…
Design
Preclinical
Authors
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Should not alter clinical antiviral approaches; leaves open whether amino acid inhibition extends to in vivo models.
Do specific amino acids and their analogues inhibit the propagation of mouse encephalomyelitis virus in tissue cultures?
L-lysine and fluorophenylalanines inhibit the propagation of mouse encephalomyelitis virus in vitro, an effect that can be partially reversed by other specific amino acids.
Pearson et al. (1952) studied this question.
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