Why the study?
Chronic heart failure is a progressive disease with high incidence, motivating evaluation of the effectiveness and safety of Xinmailong injection in patients with elevated BNP and reduced LVEF.
Does Xinmailong injection improve heart function and symptoms in patients with chronic heart failure?
Population
100 CHF patients with BNP ≥200 ng/mL and LVEF ≤45%
Comparison
Standard treatment plus Xinmailong injection vs standard treatment plus placebo
Design
Multicenter randomized double-blind placebo-controlled trial
Follow-up
5 days
Authors
Loading...
Supports adjunctive Xinmailong in chronic HFrEF; extends RCT evidence for complementary injections but needs outcome trials.
Does Xinmailong injection improve heart function and symptoms in patients with chronic heart failure?
A 5-day course of intravenous Xinmailong injection added to standard therapy improved symptoms, LVEF, and BNP in patients with chronic heart failure with reduced ejection fraction.
Xue et al. (2019) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: