Why the study?
Do higher levels of total and high-molecular-weight adiponectin prevent incident diabetes in older adults?
Do higher levels of total and high-molecular-weight adiponectin prevent incident diabetes in older adults?
Increasing concentrations of total and HMW adiponectin are associated with a non-linear, comparably lower risk of incident diabetes in older adults up to specific threshold concentrations.
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No immediate clinical implications for prevention; leaves open causality and need for interventional confirmation.
Kizer et al. (2011) studied this question.
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