Why the study?
Are higher levels of high-molecular-weight adiponectin more strongly associated with a reduced risk of incident type 2 diabetes than total adiponectin in middle-aged adults?
Are higher levels of high-molecular-weight adiponectin more strongly associated with a reduced risk of incident type 2 diabetes than total adiponectin in middle-aged adults?
Higher concentrations of both total and high-molecular-weight adiponectin are similarly associated with a lower risk of developing type 2 diabetes in middle-aged adults.
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Higher HMW adiponectin levels were associated with lower diabetes incidence similar to total adiponectin; hypothesis-generating and should not yet change practice.
Zhu et al. (2010) studied this question.
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