Why the study?
Do postural challenge and isoproterenol infusion increase QT variability in healthy adults?
Population
Healthy human adult subjects (n=19 for postural challenge, n=11 for isoproterenol infusion)
Comparison
Postural challenge and isoproterenol infusion vs Supine posture and pre-infusion baseline
Design
Other
Authors
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Sympathetic activation raises QT variability in healthy adults; leaves open its value for arrhythmia risk stratification in patients.
Do postural challenge and isoproterenol infusion increase QT variability in healthy adults?
Sympathetic activation, induced by standing or isoproterenol infusion, significantly increases QT variability in healthy adults.
Yeragani et al. (2000) studied this question.
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