Why the study?
Does standing posture alter cardiac repolarization independent of heart rate in healthy volunteers?
Does standing posture alter cardiac repolarization independent of heart rate in healthy volunteers?
Standing induces a postural effect on cardiac repolarization independent of heart rate, which may provide a physiological control to validate ECG methodology in clinical trials.
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Standing alters QTc variably by formula in healthy subjects; supports standing as a potential ECG validation control but remains hypothesis-generating.
Williams et al. (2006) studied this question.
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