June 1, 1982AJP Heart and Circulatory Physiology
Reflexes elicited by acute stretch of atrial vs. pulmonary receptors in conscious dogs
Population
Conscious dogs
Comparison
Partial obstruction of blood flow at various… vs Comparison between different obstruction sites
Design
Preclinical
Authors
Discussion
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Implication
Left atrial receptor stretch may regulate renal and hormonal responses in dogs; leaves open translation to human volume homeostasis or HF.
Structured PICO
P
Population
Conscious dogs
I
Intervention
Partial obstruction of blood flow at various sites within the thorax (inflation of a balloon in the left atrium, partial occlusion of pulmonary veins or main pulmonary artery, inflation of balloon in right atrium, constriction of thoracic inferior vena cava)
C
Comparator
Comparison between different obstruction sites
O
Outcome
Hemodynamics, renal function, and circulating hormonessurrogate
Acute stretch of left atrial receptors, but not pulmonary or right heart receptors, elicits a reflex response altering cardiovascular function, renal function, and circulating hormones in conscious dogs.
Cite This Study
Schultz et al. (1982) studied this question.