Why the study?
Systemic metabolic and cardiovascular alterations have been reported in vitiligo, but epicardial fat thickness and echocardiographic structural changes remain understudied.
Is vitiligo associated with increased epicardial fat thickness and adverse atherogenic lipid indices compared to healthy controls?
Population
90 adults with vitiligo and 90 matched controls
Comparison
Adults with vitiligo vs matched healthy controls
Design
Case-control study
Key result
Vitiligo was independently associated with increased mean epicardial fat thickness (B = 0.82, p = 0.003) and adverse triglyceride-related atherogenic indices compared to healthy controls.
Authors
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May warrant EFT screening in vitiligo; leaves open causal ties to severity or progression.
Case-Control (n=180)
Is vitiligo associated with increased epicardial fat thickness and adverse atherogenic lipid indices compared to healthy controls?
Effect estimate: B = 0.82
p-value: p=0.003
Vitiligo is independently associated with increased epicardial fat thickness and adverse atherogenic lipid profiles, suggesting a higher subclinical cardiovascular risk in these patients.
Esen et al. (2026) conducted a case-control in Vitiligo (n=180). Vitiligo vs. Healthy controls was evaluated on Mean Epicardial Fat Thickness (EFT) (B = 0.82, p=0.003). Vitiligo was independently associated with increased mean epicardial fat thickness (B = 0.82, p = 0.003) and adverse triglyceride-related atherogenic indices compared to healthy controls.
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