Why the study?
Are KCNJ11 and ABCC8 gene polymorphisms associated with differences in echocardiographic parameters in patients with chronic heart failure?
Are KCNJ11 and ABCC8 gene polymorphisms associated with differences in echocardiographic parameters in patients with chronic heart failure?
Specific genetic polymorphisms in ATP-sensitive potassium channel subunits are associated with significant differences in left ventricular mass and end-diastolic volume in patients with ischemic chronic heart failure.
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Suggests genetic modulation of LV remodeling in CHF; hypothesis-generating and should not yet change practice.
Strutynskyi et al. (2018) studied this question.
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