Population
Pig model (n=10)
Comparison
Acute unilateral complete ureteral obstruction… vs Sham-operated group
Design
Preclinical
Follow-up
15 hours
Authors
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Supports intrarenal angiotensin II generation after ureteral obstruction in pigs; leaves open clinical translation.
Acute unilateral ureteral obstruction in pigs significantly reduces renal blood flow and increases intrarenal de novo generation of angiotensin II.
Frøkiær et al. (1992) studied this question.
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