Why the study?
Does a Thrombelastograph (TEG) ecarin clotting time (ECT) assay improve correlation to bivalirudin plasma levels compared to a standard ACT assay in patients undergoing interventional cardiology procedures?
Population
n=80 patients undergoing interventional cardiology procedures with bivalirudin anticoagulation
Comparison
Thrombelastograph ecarin clotting time assay vs Standard Hemochron activated clotting time assay…
Design
Cross-sectional
Authors
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TEG ECT may support better bivalirudin monitoring than ACT in procedures; hypothesis-generating and should not yet change practice.
Does a Thrombelastograph (TEG) ecarin clotting time (ECT) assay improve correlation to bivalirudin plasma levels compared to a standard ACT assay in patients undergoing interventional cardiology procedures?
The TEG ECT assay demonstrates a significantly stronger correlation with bivalirudin plasma levels than the standard ACT assay, suggesting it may be more useful for monitoring anticoagulation during interventional procedures.
Carroll et al. (2006) studied this question.
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