Key result
The diagnosis of malignant fibrous histiocytoma should be restricted to pleomorphic sarcomas lacking a specific line of differentiation, often requiring immunohistochemistry or electron microscopy.
Design
Review
Authors
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May refine pleomorphic sarcoma classification in practice; leaves open multicenter validation of ancillary testing protocols.
Highlights the evolving diagnostic criteria and classification of malignant fibrous histiocytoma, emphasizing the need for immunohistochemistry or electron microscopy to identify lines of differentiation.
Al‐Agha et al. (2008) conducted a review in Malignant fibrous histiocytoma. The diagnosis of malignant fibrous histiocytoma should be restricted to pleomorphic sarcomas lacking a specific line of differentiation, often requiring immunohistochemistry or electron microscopy.
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