Key result
No clinical study data is present in the provided text.
Population
21 patients with dominant aortic stenosis and 17 well-matched patients with dominant aortic insufficiency…
Design
Case-control
Authors
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Coagulation activation may contribute to aortic stenosis progression; hypothesis-generating and should not yet change practice.
Fibrin and tissue factor are significantly increased in calcified stenotic aortic valves compared to insufficient valves, and correlate with systemic thrombin generation, suggesting coagulation may contribute to aortic stenosis progression.
Natorska et al. (2010) studied this question. No clinical study data is present in the provided text.
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