Key result
In patients with essential hypertension, left ventricular diastolic dysfunction (E/E' > 15) was associated with an 8.31-fold higher odds of having Stage 3 chronic kidney disease compared to normal diastolic function.
Population
207 patients with essential hypertension from a single center in China. Key exclusions: atrial fibrillation…
Design
Cross-sectional
Authors
Loading...
May warrant integrated cardio-renal evaluation in hypertension; leaves open causality and requires prospective validation.
Cross-Sectional (n=207)
No
Odds Ratio: 8.31 (95% CI 2–34.56)
p-value: p=0.0036
In patients with essential hypertension, left ventricular diastolic dysfunction (E/E' >15) and elevated NT-proBNP are significantly associated with reduced glomerular filtration rate and increased albuminuria.
Yang et al. (2013) conducted a cross-sectional in Essential hypertension (n=207). Left ventricular diastolic dysfunction (E/E' > 15) vs. Normal LV diastolic function (E/E' ≤ 10) was evaluated on Stage 3 chronic kidney disease (GFR 30-59 ml/min/1.73 m2) (OR 8.31, 95% CI 2.00-34.56, p=0.0036). In patients with essential hypertension, left ventricular diastolic dysfunction (E/E' > 15) was associated with an 8.31-fold higher odds of having Stage 3 chronic kidney disease compared to normal diastolic function.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: