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Supports filtration-reabsorption of plasma proteins in rats; leaves open extension to human proteinuria mechanisms.
SummaryProteinuria was found to be a usual occurrence in albino rats, with an average excretion during fasting of 3.0 mg of globulin and 3.3 mg of albumin in 24 hours. Marked variation in the daily urinary protein excretion was observed. Evidence is obtained indicating glomerular filtration and tubular reabsorption of an Evans blue-plasma protein complex, and, by inference, of normal plasma protein. Such tubular reabsorption possibly involves the mitochondria of the tubular cells.
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S. B. Gilso (1949) studied this question.
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