What question did this study set out to answer?

The aim is to identify patients at high risk of developing diabetic nephropathy using urinary albumin excretion rates.

Early detection of patients at risk of developing diabetic nephropathy. A longitudinal study of urinary albumin excretion

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The aim is to identify patients at high risk of developing diabetic nephropathy using urinary albumin excretion rates.
Longitudinal study conducted on insulin-dependent diabetics without proteinuria.
Urinary albumin excretion measured using radial immunodiffusion.
Follow-up period of 6 years to monitor changes in albumin excretion, serum creatinine, and blood pressure.
Five patients showed elevated urinary albumin excretion, later developing persistent albuminuria (132 to 1007 mg/24 h, P < 0.05).
Increased serum creatinine from 83 to 128 μmol/l, P < 0.05, and raised blood pressure from 135/86 to 163/112 mmHg, P < 0.05, were observed.
Fifteen patients maintained normal urinary albumin excretion levels throughout the study with minimal changes.

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Longitudinal study identifies patients at risk of diabetic nephropathy through urinary albumin monitoring, suggesting early intervention strategies.

Parving et al. (1982) studied this question.

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Longitudinal study identifies patients at risk of diabetic nephropathy through urinary albumin monitoring, suggesting early intervention strategies.