Key result
Albumin excretion rate measurement identified microalbuminuria in 27% and macroproteinuria in 7% of 276 patients, with quantitative immunoassay preferred over semiquantitative tests.
Why the study?
Does quantitative immunoassay provide better diagnostic value than semiquantitative tests for the early detection of diabetic nephropathy in clinical practice?
Population
276 patients (including patients with type I and type II diabetes mellitus)
Comparison
Measurement of albumin excretion rate using a… vs Semiquantitative tests
Design
Cross-sectional
Authors
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May favor quantitative immunoassay for diabetic nephropathy screening; leaves open need for prospective outcome trials.
Observational (n=276)
Does quantitative immunoassay provide better diagnostic value than semiquantitative tests for the early detection of diabetic nephropathy in clinical practice?
Quantitative immunoassay based on a 24-hour urine sample is preferable to semiquantitative tests for the early detection of diabetic nephropathy in routine clinical practice.
M. J. McKenna (1991) conducted an observational in Diabetic nephropathy (n=276). Albumin excretion rate measurement was evaluated on Albumin excretion rate categories. Albumin excretion rate measurement identified microalbuminuria in 27% and macroproteinuria in 7% of 276 patients, with quantitative immunoassay preferred over semiquantitative tests.
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