Why the study?
Does ibopamine alone or with captopril improve beta-adrenoceptor density and hemodynamics in a rat model of chronic myocardial infarction?
Does ibopamine alone or with captopril improve beta-adrenoceptor density and hemodynamics in a rat model of chronic myocardial infarction?
In a rat model of chronic MI, combined treatment with ibopamine and captopril increased myocardial beta-adrenoceptor density and reduced norepinephrine levels without improving hemodynamics.
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Should not change post-MI practice; hypothesis-generating for combined effects on beta-adrenoceptor density in animal models.
Veldhuisen et al. (1995) studied this question.
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