Key result
Statin therapy has an unclarified and discordant role in preventing the degeneration of aortic biological prostheses, highlighting the need for large, prospective investigations.
Why the study?
Do statins prevent the degeneration of aortic biological prostheses?
Do statins prevent the degeneration of aortic biological prostheses?
Preliminary reports suggest statins may reduce the degeneration of aortic valve bioprostheses, but further data is needed to prove this hypothesis.
Current data do not support statins to prevent bioprosthetic degeneration; leaves open a possible benefit awaiting definitive trials.
It has been recently observed that statins might slow the progression of aortic stenosis or sclerosis. Preliminary reports suggested a similar positive effect in reducing the degeneration of aortic valve bioprostheses even though this hypothesis should be further proven and supported by new data. In this review the present evidences of the possible effects of statins in this field are discussed.
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Antonini‐Canterin et al. (2006) conducted a review in Aortic biological prostheses degeneration. Statins vs. No statin therapy was evaluated. Statin therapy has an unclarified and discordant role in preventing the degeneration of aortic biological prostheses, highlighting the need for large, prospective investigations.
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