Key result
Genomic characterization of enterovirus A71 and coxsackievirus A16 isolates from Lao patients in 2011 revealed they were related to genotype C4 and B1a, respectively, circulating in the region.
Observational
First genomic characterization of EV-A71 and CV-A16 in Lao PDR confirms regional circulation of specific genotypes.
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May guide Lao enterovirus surveillance; leaves open questions on local transmission and clinical impact.
Enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) are major aetiological agents of hand, foot and mouth disease in Asia. We established the first genomic characterization of strains isolated in 2011 from Lao patients. Isolates were related to EV-A71 genotype C4 and CV-A16 genotype B1a that circulated in neighbouring countries during the same period. This confirms the regional character of hand, foot and mouth disease epidemiology and makes plausible the occurrence of severe disease in the Lao population.
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Nguyễn et al. (2014) conducted an observational in Hand, foot and mouth disease. Genomic characterization of EV-A71 and CV-A16 isolates was evaluated on Genomic characterization of strains. Genomic characterization of enterovirus A71 and coxsackievirus A16 isolates from Lao patients in 2011 revealed they were related to genotype C4 and B1a, respectively, circulating in the region.
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