Key result
The low-sodium, high-potassium diet produced a significantly greater reduction in systolic blood pressure among participants on antihypertensive therapy (26.2 mmHg) compared to those not on therapy (22.8 mmHg).
Why the study?
Does a low-sodium high-potassium diet or DASH-type diet reduce blood pressure in adults on antihypertensive therapy compared to those not on therapy?
Population
94 adults over 25 years of age with blood pressure >= 120/80 mmHg or >= 116/78 mmHg, mean age 55.6, 38…
Comparison
Two 4-week dietary regimens consumed in random… vs A 2-week control diet consumed before each test…
Design
RCT, consumed two 4-week dietary regimens in random order
Follow-up
4 weeks per diet phase
Authors
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Augments SBP reduction with antihypertensive therapy; extends dietary intervention evidence to medicated hypertension populations.
RCT (n=94)
Open-label
Random order
Does a low-sodium high-potassium diet or DASH-type diet reduce blood pressure in adults on antihypertensive therapy compared to those not on therapy?
Absolute Event Rate: 26.2% vs 22.8%
p-value: p=0.036
A low-sodium, high-potassium diet significantly enhances the blood pressure-lowering effect of antihypertensive medications, particularly renin-angiotensin system blockers.
Huggins et al. (2010) conducted an RCT in Elevated blood pressure / Hypertension (n=94). Low-sodium high-potassium (LNAHK) diet vs. Control diet (low-K, low-Ca) was evaluated on Fall in systolic blood pressure (SBP) compared to control diet (p=0.036). The low-sodium, high-potassium diet produced a significantly greater reduction in systolic blood pressure among participants on antihypertensive therapy (26.2 mmHg) compared to those not on therapy (22.8 mmHg).
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