Key result
Women with brachial artery flow-mediated vasodilation <12% had a significantly shorter exercise time compared to those with FMD ≥12% (411 vs 482 seconds, P=0.014).
Why the study?
Does peripheral vascular endothelial function correlate with exercise capacity in women without ischemic heart disease?
Population
Women referred for clinically indicated exercise testing with technetium-99 myocardial perfusion imaging…
Design
Cross-sectional
Authors
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Impaired FMD may flag reduced exercise capacity in women without IHD; leaves open whether endothelial assessment refines fitness evaluation or warrants trials.
Observational (n=105)
Does peripheral vascular endothelial function correlate with exercise capacity in women without ischemic heart disease?
Effect estimate: r = 0.34
Absolute Event Rate: 411% vs 482%
p-value: p=0.014
Brachial artery flow-mediated vasodilation correlates with exercise capacity in women, independent of age and BMI, even in the absence of ischemic heart disease.
Patel et al. (2005) conducted an observational in Referred for exercise testing without ischemic heart disease (n=105). Brachial artery flow-mediated vasodilation (FMD) < 12% vs. FMD ≥ 12% was evaluated on Duration of exercise on a symptom-limited Bruce protocol (seconds) (r = 0.34, p=0.014). Women with brachial artery flow-mediated vasodilation <12% had a significantly shorter exercise time compared to those with FMD ≥12% (411 vs 482 seconds, P=0.014).
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