Key result
The ESC HF III Registry enrolled 10,162 patients with heart failure across 41 countries to characterize clinical features, assess implementation of guideline-recommended therapy, and evaluate outcomes.
Why the study?
Heart failure outcomes remain poor despite advances in therapy, prompting the need to characterize HF clinical features and outcomes and assess guideline-recommended therapy implementation.
Observational (n=10,162)
Yes
The ESC HF III Registry is designed to provide comprehensive insights into contemporary heart failure characteristics, treatment implementation, and outcomes across 41 countries.
Contemporary HF registry data underscore ongoing high event rates; leaves open how best to close GDMT implementation gaps across phenotypes.
AIMS: Heart failure outcomes remain poor despite advances in therapy. The European Society of Cardiology Heart Failure III Registry (ESC HF III Registry) aims to characterize HF clinical features and outcomes and to assess implementation of guideline-recommended therapy in Europe and other ESC affiliated countries. METHODS: Between 1 November 2018 and 31 December 2020, 10 162 patients with chronic or acute/worsening HF with reduced, mildly reduced, or preserved ejection fraction were enrolled from 220 centres in 41 European or ESC affiliated countries. The ESC HF III Registry collected data on baseline characteristics (hospital or clinic presentation), hospital course, diagnostic and therapeutic decisions in hospital and at the clinic visit; and on outcomes at 12-month follow-up. These data include demographics, medical history, physical examination, biomarkers and imaging, quality of life, treatments, and interventions - including drug doses and reasons for non-use, and cause-specific outcomes. CONCLUSION: The ESC HF III Registry will provide comprehensive and unique insight into contemporary HF characteristics, treatment implementation, and outcomes, and may impact implementation strategies, clinical discovery, trial design, and public policy.
No takes yet. Share an insight, caveat, or question.
Lund et al. (2023) conducted an observational in Heart failure (n=10,162). Contemporary heart failure care was evaluated. The ESC HF III Registry enrolled 10,162 patients with heart failure across 41 countries to characterize clinical features, assess implementation of guideline-recommended therapy, and evaluate outcomes.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: