Key result
Upgrading from an ICD to a CRT-defibrillator did not significantly change the frequency of non-sustained ventricular arrhythmias (58.51 vs 2.38 per patient per month, p=0.66).
Why the study?
Does upgrading from an ICD to a CRT-defibrillator reduce the frequency of ventricular arrhythmias in patients with heart failure?
Population
52 patients, aged 70 years, who underwent upgrade from an implantable cardioverter defibrillator to a…
Comparison
Upgrade of ICD to CRT-defibrillator vs Patient's own baseline prior to CRT upgrade
Design
Cohort
Authors
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ICD-to-CRT upgrade was not associated with reduced non-sustained ventricular arrhythmias; leaves open resynchronization effects on arrhythmia burden in heart failure.
Cohort (n=52)
No
Does upgrading from an ICD to a CRT-defibrillator reduce the frequency of ventricular arrhythmias in patients with heart failure?
Absolute Event Rate: 58.51% vs 2.38%
p-value: p=0.66
Upgrading from an ICD to a CRT-defibrillator improves ejection fraction but does not significantly decrease the frequency of ventricular arrhythmias or appropriate device therapies.
Lin et al. (2007) conducted a cohort in Heart failure and left ventricular dysfunction (n=52). Upgrade of ICD to CRT-defibrillator vs. Prior to upgrade (baseline) was evaluated on Frequency of ventricular arrhythmias prior to and following upgrade to CRT device (p=0.66). Upgrading from an ICD to a CRT-defibrillator did not significantly change the frequency of non-sustained ventricular arrhythmias (58.51 vs 2.38 per patient per month, p=0.66).
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