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August 1, 1999Vascular Medicine

Kawasaki disease

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Population

Children (predominantly infancy and early childhood, rarely teenagers) with Kawasaki disease in the USA.

Design

Review

Authors

Jane W. Newburger
Jane W. NewburgerPediatric Cardiology
JBJane C. BurnsPediatric / Congenital Cardiology

Discussion

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Implication

Supports acute IVIG in Kawasaki disease; leaves open optimal dosing and long-term surveillance needs.

Structured PICO

P
Population
Children (predominantly infancy and early childhood, rarely teenagers) with Kawasaki disease in the USA.
I
Intervention
Intravenous gamma globulin, 2 g per kg, in the acute phase

Kawasaki disease requires acute treatment with IVIG to reduce coronary aneurysm risk and mandates long-term surveillance with myocardial imaging.

Cite This Study

Newburger et al. (1999) studied this question.

synapsesocial.com/papers/6a85b21c8018c50ef23db167https://doi.org/10.1177/1358836x9900400310
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Epidemiologic Pictures of Kawasaki Disease in Japan: From the Nationwide Incidence Survey in 1991 and 19921995 · 124 citations
  2. 2Clonal expansion of CD8+ T cells in Kawasaki disease1997 · 105 citations
  3. 3Diagnosis and therapy of Kawasaki disease in children.1993 · 529 citations
  4. 4Pathology of the Heart in Kawasaki Disease1978 · 556 citations