Key result
Implantation of a leadless pacemaker providing atrioventricular synchronous pacing in an immunosuppressed heart transplant patient resulted in stable pacing parameters and no recurrence of syncope at 8 months.
Case Report (n=1)
No
A leadless pacemaker with atrioventricular synchronous pacing can be safely and effectively used in an immunocompromised heart transplant patient with high-grade AV block to mitigate infection risk.
May support leadless AV synchronous pacing to reduce infection risk in transplant recipients; leaves open need for prospective data.
We report the first leadless pacemaker (L-PM) providing atrioventricular synchronous pacing implanted into a heart transplant patient receiving chronic immunosuppressive therapy. The patient presented with syncope corresponding to sinus rhythm with high-grade atrioventricular block. Previously, L-PMs provided only single-chamber ventricular sensing and pacing. A Micra AV lL-PM provides atrioventricular synchronous pacing by tracking mechanical atrial contraction. L-PMs, which now support broader indications, should be considered in patients at greater risk of infection.
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Mistry et al. (2021) conducted a case report in High-grade atrioventricular block in a heart transplant patient (n=1). Leadless pacemaker with atrioventricular synchronous pacing (Micra AV) was evaluated on Device function and clinical symptoms (syncope). Implantation of a leadless pacemaker providing atrioventricular synchronous pacing in an immunosuppressed heart transplant patient resulted in stable pacing parameters and no recurrence of syncope at 8 months.
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