Exercise intolerance in chronic heart failure: mechanisms and therapies. Part II
Population
Patients with chronic heart failure experiencing exercise intolerance
Design
Review
Authors
Discussion
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Implication
Supports multifactorial HF exercise intolerance beyond cardiac output; leaves open targeted trials on reflexes and cachexia.
Structured PICO
P
Population
Patients with chronic heart failure experiencing exercise intolerance (muscular fatigue and dyspnoea on exertion)
This review highlights the multifactorial origin of exercise intolerance in chronic heart failure, emphasizing the roles of excitatory reflexes and cardiac cachexia beyond just cardiac dysfunction.
Cite This Study
Piepoli et al. (2010) studied this question.