Why the study?
Do angiotensin II and angiotensin III attenuate vagal nerve-induced decreases in heart rate in animal models?
Population
Intact dogs and isolated guinea-pig atria
Comparison
Angiotensin II and angiotensin III vs Control (absence of angiotensin II and III)
Design
Preclinical
Authors
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These animal findings require human validation; leaves open clinical relevance for vagal heart rate control.
Do angiotensin II and angiotensin III attenuate vagal nerve-induced decreases in heart rate in animal models?
Angiotensin II and III attenuate the heart rate-lowering effects of vagal nerve stimulation in preclinical models.
Erica K. Potter (1982) studied this question.
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